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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PXN
All Species:
38.79
Human Site:
S533
Identified Species:
71.11
UniProt:
P49023
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49023
NP_001074324.1
591
64533
S533
H
Y
H
E
R
R
G
S
L
C
S
G
C
Q
K
Chimpanzee
Pan troglodytes
XP_001159942
589
64154
S531
H
Y
H
E
R
R
G
S
L
C
S
G
C
Q
K
Rhesus Macaque
Macaca mulatta
XP_001085795
563
61555
S505
H
Y
H
E
R
R
G
S
L
C
S
G
C
Q
K
Dog
Lupus familis
XP_543425
664
72715
S606
H
Y
H
E
R
R
G
S
L
C
S
G
C
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8VI36
591
64458
S533
H
Y
H
E
R
R
G
S
L
C
S
G
C
Q
K
Rat
Rattus norvegicus
Q66H76
586
64001
S528
H
Y
H
E
R
R
G
S
L
C
S
G
C
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P49024
559
61224
S501
H
Y
H
E
R
R
G
S
L
C
S
G
C
Q
K
Frog
Xenopus laevis
Q2TCH4
506
55983
R460
C
E
Q
P
I
T
G
R
C
V
T
A
M
G
K
Zebra Danio
Brachydanio rerio
Q6P7E4
419
45574
D373
D
F
K
I
D
A
G
D
R
F
L
E
A
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523601
581
64668
S523
H
Y
H
A
K
R
G
S
L
C
A
G
C
S
K
Honey Bee
Apis mellifera
XP_624308
559
62451
S501
H
Y
H
A
K
R
G
S
L
C
A
G
C
H
K
Nematode Worm
Caenorhab. elegans
Q09476
413
46434
A367
I
N
G
R
C
V
A
A
M
G
R
K
F
H
P
Sea Urchin
Strong. purpuratus
XP_780574
695
76058
S637
H
Y
H
A
V
R
G
S
L
C
A
G
C
N
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
92.5
83.1
N.A.
93.7
74.9
N.A.
N.A.
84.7
41.2
21.6
N.A.
43.1
43.3
33.8
43.4
Protein Similarity:
100
99.1
92.8
85.2
N.A.
95.7
78.3
N.A.
N.A.
88.4
54.3
36.5
N.A.
54.8
57
47
56.2
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
13.3
6.6
N.A.
73.3
73.3
0
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
20
13.3
N.A.
86.6
86.6
13.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
24
0
8
8
8
0
0
24
8
8
0
0
% A
% Cys:
8
0
0
0
8
0
0
0
8
77
0
0
77
0
0
% C
% Asp:
8
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
0
8
0
54
0
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
8
0
0
8
0
0
% F
% Gly:
0
0
8
0
0
0
93
0
0
8
0
77
0
8
8
% G
% His:
77
0
77
0
0
0
0
0
0
0
0
0
0
16
0
% H
% Ile:
8
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
8
0
16
0
0
0
0
0
0
8
0
0
85
% K
% Leu:
0
0
0
0
0
0
0
0
77
0
8
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
0
0
54
0
% Q
% Arg:
0
0
0
8
54
77
0
8
8
0
8
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
77
0
0
54
0
0
8
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% T
% Val:
0
0
0
0
8
8
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
77
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _